Management of Opioid Addiction With Opioid Substitution Treatments: Beyond Methadone and Buprenorphine
نویسندگان
چکیده
منابع مشابه
Managing opioid addiction with buprenorphine.
Legislation has enabled physicians to treat opioid-dependent patients with an office-based maintenance program using buprenorphine, a partial mu-opioid receptor agonist. Clinical studies indicate buprenorphine effectively manages opioid addiction. Buprenorphine is more effective than placebo for managing opioid addiction but may not be superior to methadone if high doses are needed. It is compa...
متن کاملManaging opioid dependence. Comparing buprenorphine with methadone.
analysis comparing the effectiveness of buprenorphine and methadone. Research question Is buprenorphine as effective as methadone for managing opioid dependence? Type of article and design Meta-analysis by three reviewers. Relevance to family physicians Community-based family physicians are uniquely suited to care for opioid-dependent patients. Buprenorphine, like methadone, is a substitution t...
متن کاملA preliminary study comparing methadone and buprenorphine in patients with chronic pain and coexistent opioid addiction.
Patients with opioid addiction who receive prescription opioids for treatment of nonmalignant chronic pain present a therapeutic challenge. Fifty-four participants with chronic pain and opioid addiction were randomized to receive methadone or buprenorphine/naloxone. At the 6-month follow-up examination, 26 (48.1%) participants who remained in the study noted a 12.75% reduction in pain (P = 0.04...
متن کاملMortality risk of opioid substitution therapy with methadone versus buprenorphine: a retrospective cohort study.
BACKGROUND Opioid dependence increases risk of premature mortality. Opioid substitution therapy with methadone or buprenorphine reduces mortality risk, especially for drug-related overdose. Clinical guidelines recommend methadone as the first line of opioid substitution therapy. We aimed to test whether buprenorphine treatment has a lower mortality risk than does methadone treatment by comparin...
متن کاملDiversion of methadone and buprenorphine from opioid substitution treatment: the importance of patients' attitudes and norms.
AIMS Methadone and buprenorphine diversion by patients in opioid substitution treatment (OST) is a poorly understood phenomenon. We study the norms and attitudes on diversion among OST patients, including the role these norms and attitudes play as diversion risk factors. We also study whether perceived quality of care, social bonds to treatment staff, and deterrence can be associated with diver...
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ژورنال
عنوان ژورنال: Frontiers in Psychiatry
سال: 2019
ISSN: 1664-0640
DOI: 10.3389/fpsyt.2018.00742